Our newest product is dropping soon
Sign up for early access to our latest derm-created, 100% clinically-proven innovation. Shop before everyone else on Sunday, 9/15.
The Holiday Shop is here, save up to 40%
Shop NowCouldn't load pickup availability
hydrating
soothing
clinically-Proven
A NEW 3-step program by dermatologist Dr. Whitney Bowe that complements in-office procedures, enhancing results and expediting recovery. It also serves as a daily routine for even the most sensitive skin—boosting hydration and resilience while visibly smoothing, firming, and lifting. Saves you 17%.
Features 2x bestsellers and NEW P46™ Serum:
Non-comedogenic, vegan, gluten-free, cruelty-free, and suitable for sensitive, post-procedure skin. Expertly addresses skin changes due to perimenopause or menopause.
*see clinical section for study design.

When using Procedure Enhancement Program
100%
said this program helped their skin recover faster following their in-office procedure
100%
said skin feels soothed and appears less red after using this program post-procedure
100%
said their skin barrier feels stronger and more resilient
94%
said this program made skin more hydrated and glowy
When using Procedure Enhancement Program
100%
said this program helped their skin recover faster following their in-office procedure
100%
said skin feels soothed and appears less red after using this program post-procedure
100%
said their skin barrier feels stronger and more resilient
94%
said this program made skin more hydrated and glowy
When using Procedure Enhancement Program
100%
said this program helped their skin recover faster following their in-office procedure
100%
said skin feels soothed and appears less red after using this program post-procedure
100%
said their skin barrier feels stronger and more resilient
94%
said this program made skin more hydrated and glowy
When using Procedure Enhancement Program
100%
said this program helped their skin recover faster following their in-office procedure
100%
said skin feels soothed and appears less red after using this program post-procedure
100%
said their skin barrier feels stronger and more resilient
94%
said this program made skin more hydrated and glowy
When using Procedure Enhancement Program
100%
said this program helped their skin recover faster following their in-office procedure
100%
said skin feels soothed and appears less red after using this program post-procedure
100%
said their skin barrier feels stronger and more resilient
94%
said this program made skin more hydrated and glowy
100%
said this program helped their skin recover faster following their in-office procedure
100%
said skin feels soothed and appears less red after using this program post-procedure
100%
said their skin barrier feels stronger and more resilient
94%
said this program made skin more hydrated and glowy
Key Ingredients
How to Use
Procedure Enhancement ProgramImmediately following your procedure,
Step 1: Apply 3 to 4 pumps of P46™ Peptide + HA Plumping Serum onto the face, neck, and chest to hydrate and reduce redness.
Step 2: Apply Bowe Glowe™ Cream generously to your face, neck, and chest to strengthen the skin barrier.
Start the full program the evening of your procedure. If you're using the program without getting a procedure, follow the below steps every morning and night.
Step 1: Massage Bowe Glowe Cleanser onto damp skin using circular motions before rinsing it off completely. Remember, a little goes a long way.
Step 2: Apply 3 to 4 pumps of P46™ Peptide + HA Plumping Serum onto the face, neck, and chest.
Step 3: Apply Bowe Glowe™ Cream generously to your face, neck, and chest.
Immediately following your procedure,
Step 1: Apply 3 to 4 pumps of P46™ Peptide + HA Plumping Serum onto the face, neck, and chest to hydrate and reduce redness.
Step 2: Apply Bowe Glowe™ Cream generously to your face, neck, and chest to strengthen the skin barrier.
Start the full program the evening of your procedure. If you're using the program without getting a procedure, follow the below steps every morning and night.
Step 1: Massage Bowe Glowe Cleanser onto damp skin using circular motions before rinsing it off completely. Remember, a little goes a long way.
Step 2: Apply 3 to 4 pumps of P46™ Peptide + HA Plumping Serum onto the face, neck, and chest.
Step 3: Apply Bowe Glowe™ Cream generously to your face, neck, and chest.
How to layer your Procedure Enhancement Program
LEARN MORE ABOUT SKIN CYCLING
Sustainability
Sustainable Materials
Component uses post-consumer recycled (PCR) plastic, and all products are housed in FSC®️-certified cartons and recyclable shippers.
Airless Technology
Airless pumps maximize how much formula you get out of your bottle, plus protect your skincare from oxygen—keeping it potent and effective.
Eco-Friendly Refills
Run out, refill, then reuse our glass bottles. Keep and reuse your top pump, it connects to this refill tube.
Sustainable Materials
Cruelty-Free Formulas
Up to 27% decrease in skin sagging (i)
Up to 25% decrease in fine lines + wrinkles (i)
Up to 42% increase in skin firmness (i)
Up to 33% increase in skin elasticity (i)
Up to 42% increase in skin smoothness (i)
Up to 25% increase in skin plumpness (i)
Up to 55% increase in skin brightness / luminosity (i)
Floods skin with up to 2.8x the hydration (ii)
96% would recommend P46™ to a friend (iii)
100% said P46™ reduced visible redness in their post-procedure skin (iv)
(i) independent clinical study, 25 subjects who used P46™ 2x daily, measured at the 12-week time point.
(ii) independent CORNEOMETER® clinical study, 25 subjects who used P46™, measured at the immediate time point.
(iii) Clinical study, 25 subjects who used P46™ 2x daily, 1-week time point.
(iv) 4-week clinical study of 14 subjects who used P46™2x daily, 4-week time-point, following professional in-office procedure.
(v) 4-week ongoing clinical study of 17 subjects who used PEP 2x daily at the 4-week time point, following professional in-office procedures.
100% said Bowe Glowe Cleanser was soothing on their post-procedure skin (i)
100% agreed Bowe Glowe Cleanser helped their post-procedure skin recover faster (i)
93% said their skin overall appears more healthy and balanced (ii)
96% said their skin looks and feels softer and smoother (ii)
96% said their skin looks brighter and more radiant (iii)
(i) 1-week clinical study of 11 subjects who used BGC at the overnight time point following professional in-office procedures.
(ii) 1-week independent clinical study of 32 subjects who used Bowe Glowe Cleanser at the 1-week time point.
(iii) 1-week independent clinical study of 32 subjects who used Bowe Glowe Cleanser at the immediate time point.
100% showed a clinically-measured increase in skin hydration within minutes (i)
97% said fine lines and wrinkles appeared smoother (ii)
97% said skin looks and feels healthier than ever before (ii)
97% said they felt more confident in their skin (ii)
93% said skin had a healthy glow (iii)
97% agreed Bowe Glowe works well under makeup (iii)
(i) 4-week independent clinical study of 32 subjects who used Bowe Growe once daily and Bowe Glowe twice daily, as measured at the 30 day time period using a Corneometer®.
(ii) 4-week independent clinical study of 30 subjects who used Bowe Glowe twice daily, measured at 4 weeks.
(iii) 4-week independent clinical study of 30 subjects who used Bowe Glowe twice daily, measured at 2 weeks.
FULL INGREDIENT LIST: Water/Aqua/Eau, Propanediol, Butylene Glycol, Squalane, Glycerin, Capryloyl Glycerin/Sebacic Acid Copolymer, Tripeptide-1, Palmitoyl Tripeptide-1, Acetyl Dipeptide-1 Cetyl Ester, Palmitoyl Tetrapeptide-7, Beta-Glucan, Polyglutamic Acid, Sodium Hyaluronate, Ethylhexyl Olivate, Sodium Lactate, Polyacrylate Crosspolymer-6, Phenoxyethanol, Pentylene Glycol, Ethylhexylglycerin, Sodium Acrylates Copolymer, Sorbitan Laurate, Sodium Phytate, Polyglyceryl-4 Oleate, Citric Acid, Hydroxyethylcellulose, Dextran, Carbomer, Caprylyl Glycol, Coco-Glucoside
FORMULATED WITHOUT:fragrance, essential oils, parabens, animal derivatives, formaldehyde-releasers, drying alcohols, phthalates, petrolatum, silicones.
FULL INGREDIENT LIST: water, sodium cocoyl isethionate, cocamidopropyl hydroxysultaine, polyglyceryl-3 methylglucose sistearate, glycerin, betaine, propanediol, glycol distearate, caprylic/capric triglyceride, cocos nucifera (coconut) oil, persea gratissima (avocado) oil, vitis vinifera (grape) seed oil, simmondsia chinensis (jojoba) seed oil, polyacrylate crosspolymer-6, xylitylglucoside, anhydroxylitol, glyceryl stearate, cetearyl alcohol, niacinamide, 1,2-hexanediol, althaea officinalis root extract, acetyl hexapeptide-49, sodium hyaluronate, ceramide NP, lactobacillus ferment, alpha-glucan oligosaccharide, cucumis sativus (cucumber) fruit extract, aloe barbadensis leaf juice, stearic acid, Oryza sativa (rice) bran extract, xylitol, inulin, rosmarinus officinalis (rosemary) leaf extract, helianthus annuus (sunflower) seed extract, tocopherol, sodium lauroyl glutamate, maltodextrin, decyl glucoside, trisodium ethylenediamine disuccinate, lauryl glucoside, ethylhexylglycerin, phenoxyethanol, butylene glycol, xanthan gum, citric acid, sodium chloride, glucose.
FORMULATED WITHOUT:synthetic fragrance, essential oils, parabens, animal derivatives, formaldehyde-releasers, drying alcohols, phthalates, petrolatum, silicones.
FULL INGREDIENT LIST: water (aqua), propanediol, caprylic/capric triglyceride, squalane, glycerin, sodium acrylates copolymer, butyrospermum parkii (shea) oil, helianthus annuus (sunflower) seed oil, punica granatum sterols, lactobacillus ferment, inulin, ceramide NP, sodium hyaluronate, alpha-glucan oligosaccharide, lecithin, bisabolol, tocopheryl acetate, hydroxydecyl ubiquinone, acrylates/C10-30 alkyl acrylate crosspolymer, ammonium acryloyldimethyltaurate/VP copolymer, maltodextrin, silica, sodium phytate, ethylhexylglycerin, phenoxyethanol, mica, titanium dioxide (CI 77891).
FORMULATED WITHOUT: fragrance, essential oils, parabens, animal derivatives, formaldehyde-releasers, drying alcohols, phthalates, petrolatum, silicones.
Use your Procedure Enhancement Program each morning, and every night of your Skin Cycling Program.
If you’re using the program immediately follow a procedure, start the full 3-step routine the evening of your treatment, and continue every morning and night. Depending on the procedure, you may be able to reintroduce your vitamin C, retinoid, or other skincare actives within just a few days post-treatment, or you may be counseled to wait a bit longer. Always consult with your healthcare professional who performed the procedure for personalized recommendations.
If you’re using the program without getting a procedure, follow this routine every morning: Bowe Glowe Cleanser, P46 Serum, Bowe Glowe Cream, sunscreen.
Each evening, start with Bowe Glowe Cleanser. Always use P46 Serum immediately after cleansing, and always end with Bowe Glowe Cream. On Exfoliation Night, apply P46 Serum before Exfoliation Night Serum. On Retinoid Night, apply P46 Serum before Retinal Night Treatment. On Recovery Night(s), apply P46 after you cleanse.
Skin Cycling is a strategic, customizable program, created by Dr. Bowe, for cycling through your evening skincare to maximize results, while minimizing irritation. Skin Cycling takes a streamlined, “smarter, not more” approach to skincare, making your products work harder and better for you. With 3.5 billion TikTok views, the viral program has influenced skincare worldwide.
Below is the Classic Skin Cycling Program, which can be customized by adding more Retinal Nights or Recovery Nights depending on your skin's needs.
Night 1: Exfoliation Night
Dr. Bowe opts for chemical exfoliating products over harsh and gritty scrubs. A chemical exfoliating serum can give your skin an immediate glow, prepping you to get the most out of night 2. Exfoliation Night™ Resurfacing + Brightening Serum is specifically formulated to push your skin outside its comfort zone, driving clinically-proven results on night 1 of your Skin Cycling Program, without harming the delicate skin barrier.
Night 2: Retinoid Night
Retinoids are one of the powerful ingredients to include in your Skin Cycling Program. They work to improve skin by breaking down dead skin cells and generating new skin cells—firming and smoothing the look of skin. Your skin’s sensitivity may influence the strength of the retinoid you choose, as some people can tolerate a retinoid more frequently than others. Retinal is the most powerful retinoid you can get without a prescription. Due to Dr. Bowe's expert formulation of Retinal Night™ Advanced 0.1% Retinal Firming Treatment, it's proven to be highly-potent and stable, yet also clinically-proven to be well-tolerated by skin. This makes Retinal Night™ perfect for leveling up any Skin Cycling Program.
Night 3 + 4: Recovery Nights
Hold off on exfoliating acids and retinoids and give your skin a chance to recover. On Recovery Nights, you want to focus on nourishing your skin microbiome and repairing your skin barrier—think hydration and moisture. Dr. Bowe developed Bowe Glowe™ Microbiome Nourishing Cream for every morning, then each night of your Skin Cycling Program, but especially for Recovery Nights to give your skin the hydration and barrier repair it needs. It has been clinically-proven to help repair the skin barrier in just one hour!*
