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firming
brightening
hydrating
The 1st dermatologist-created eye cream powered by bioengineered exosome technology, proprietary 4-CLGN™ Peptide Complex, wrinkle-relaxing neuropeptide, and vitamin C to visibly tighten, smooth, and brighten.
Immediately, the eye area is flooded with up to 3x the hydration*. Over time, skin firmness increases by up to 66%*, crepey texture is smoothed by up to 71%, and upper eyelid sagging is reduced by up to 20%*.
CLINICALLY-TESTED BENEFITS:
*See clinical section for study design

up to 66%
increase in firmness
up to 71%
decrease in crepey texture
up to 3x
immediate increase in hydration
up to 25%
decrease in fine lines & wrinkles
up to 66%
increase in firmness
up to 71%
decrease in crepey texture
up to 3x
immediate increase in hydration
up to 25%
decrease in fine lines & wrinkles
up to 66%
increase in firmness
up to 71%
decrease in crepey texture
up to 3x
immediate increase in hydration
up to 25%
decrease in fine lines & wrinkles
up to 66%
increase in firmness
up to 71%
decrease in crepey texture
up to 3x
immediate increase in hydration
up to 25%
decrease in fine lines & wrinkles
up to 66%
increase in firmness
up to 71%
decrease in crepey texture
up to 3x
immediate increase in hydration
up to 25%
decrease in fine lines & wrinkles
up to 66%
increase in firmness
up to 71%
decrease in crepey texture
up to 3x
immediate increase in hydration
up to 25%
decrease in fine lines & wrinkles
up to 3x increase in skin hydration
Up to:
66% increase in firmness
71% decrease in crepey texture
20% reduction in sagging upper eyelids
33% overall eye rejuvenation
50% increase in smoothness
37% increase in brightness
33% decrease in dark circles
16% improvement in elasticity
25% decrease in static lines + wrinkles
11% decrease in dynamic lines + wrinkles
33% reduction in puffiness
100% said Exo-Plex™ helped visibly smooth fine lines & wrinkles around the eye (v)
100% said Exo-Plex™ visibly brightened (v)
91% said Exo-Plex™ helped strengthen my skin barrier (iv)
90% said Exo-Plex™ helped visibly firm and tighten (v)
95% said Exo-Plex™ is calming and soothing (iv)
100% said Exo-Plex™ is gentle (iv)
100% said Exo-Plex™ is the perfect complement to my procedure (v)
95% said Exo-Plex™ amplified the results of their procedure (v)
95% would recommend using Exo-Plex™ post-procedure (vi)
90% said my eye area looks better than it typically does when i’m due for my next procedure (vi)
86% said Exo-Plex™ helped their skin recover more quickly post-procedure (iv)
85% said Exo-Plex™ extended the results of their procedure (vi)
(i) Based on a 12-week independent clinical study of 34 subjects who used Exo-Plex™ at the immediate time point.
(ii) Based on a 12-week independent clinical study of 34 subjects who used Exo-Plex™ 2x daily at the 12-week time point.
(iii) Based on a 12-week randomized, double-blind, placebo-controlled clinical study of 34 subjects who used Exo-Plex™ and placebo leading moisturizer 2x daily at the 12-week time point.
(iv) Based on a 3 month clinical study of 23 subjects who used Exo-Plex™ 2x daily at the 2-week timepoint following professional in-office procedure.
(v) Based on a 3 month clinical study of 21 subjects who used Exo-Plex™ 2x daily at the 4-week timepoint following professional in-office procedure.
(vi) Based on a 3 month clinical study of 21 subjects who used Exo-Plex™ 2x daily at the 12-week timepoint following professional in-office procedure.
Key Ingredients
How to Use
Exo-Plex™Apply Exo-Plex™ twice daily, AM + PM, around the entire eye area. Use a pea-sized amount (about one half of a pump), gently tapping from the inner to outer eye area, including the upper eyelid just beneath the brow/brow bone. Avoid direct contact with the eye and lash line.
Suitable for use after in-office treatments on even sensitive and post-procedure skin.
Apply Exo-Plex™ twice daily, AM + PM, around the entire eye area. Use a pea-sized amount (about one half of a pump), gently tapping from the inner to outer eye area, including the upper eyelid just beneath the brow/brow bone. Avoid direct contact with the eye and lash line.
Suitable for use after in-office treatments on even sensitive and post-procedure skin.
How to use Exo-Plex™ when Skin Cycling
LEARN MORE ABOUT SKIN CYCLING
Sustainability
Sustainable Materials
Components use post-industrial recycled (PIR) glass and post-consumer recycled (PCR) plastic. All products are housed in FSC®️-certified cartons and recyclable shippers.
Airless Technology
Airless pumps maximize how much formula you get out of your bottle, plus protect your skincare from oxygen—keeping it potent and effective.
Eco-Friendly Refills
Run out, refill, then reuse our glass bottles. Keep and reuse your top pump, it connects to this refill tube.
Sustainable Materials
Cruelty-Free Formulas
up to 3x increase in skin hydration
Up to:
66% increase in firmness
71% decrease in crepey texture
20% reduction in sagging upper eyelids
33% overall eye rejuvenation
50% increase in smoothness
37% increase in brightness
33% decrease in dark circles
16% improvement in elasticity
25% decrease in static lines + wrinkles
11% decrease in dynamic lines + wrinkles
33% reduction in puffiness
100% said Exo-Plex™ helped visibly smooth fine lines & wrinkles around the eye (v)
100% said Exo-Plex™ visibly brightened (v)
91% said Exo-Plex™ helped strengthen my skin barrier (iv)
90% said Exo-Plex™ helped visibly firm and tighten (v)
95% said Exo-Plex™ is calming and soothing (iv)
100% said Exo-Plex™ is gentle (iv)
100% said Exo-Plex™ is the perfect complement to my procedure (v)
95% said Exo-Plex™ amplified the results of their procedure (v)
95% would recommend using Exo-Plex™ post-procedure (vi)
90% said my eye area looks better than it typically does when i’m due for my next procedure (vi)
86% said Exo-Plex™ helped their skin recover more quickly post-procedure (iv)
85% said Exo-Plex™ extended the results of their procedure (vi)
(i) Based on a 12-week independent clinical study of 34 subjects who used Exo-Plex™ at the immediate time point.
(ii) Based on a 12-week independent clinical study of 34 subjects who used Exo-Plex™ 2x daily at the 12-week time point.
(iii) Based on a 12-week randomized, double-blind, placebo-controlled clinical study of 34 subjects who used Exo-Plex™ and placebo leading moisturizer 2x daily at the 12-week time point.
(iv) Based on a 3 month clinical study of 23 subjects who used Exo-Plex™ 2x daily at the 2-week timepoint following professional in-office procedure.
(v) Based on a 3 month clinical study of 21 subjects who used Exo-Plex™ 2x daily at the 4-week timepoint following professional in-office procedure.
(vi) Based on a 3 month clinical study of 21 subjects who used Exo-Plex™ 2x daily at the 12-week timepoint following professional in-office procedure.
FULL INGREDIENT LIST: Water/Aqua/Eau, Squalane, Propanediol, Glycerin, Sorbitol, Dicaprylyl Carbonate, Butylene Glycol, C10-18 Triglycerides, Punica Granatum Sterols, Rosa Canina Seed Oil, Vitis Vinifera (Grape) Seed Oil, Glyceryl Stearate SE, Tetrahexyldecyl Ascorbate, Polyglyceryl-3 Rice Branate, PEG-240/HDI Copolymer Bis-Decyltetradeceth-20 Ether, Chlamydomonas Reinhardtii Extract, Tripeptide-1, Palmitoyl Tripeptide-1, Acetyl Dipeptide-1 Cetyl Ester, Palmitoyl Tetrapeptide-7, Beta-Glucan, Acetyl Hexapeptide-8, Sodium Polyglutamate, Sodium Hyaluronate, Astaxanthin, Haematococcus Pluvialis Oil, Caffeine, Coffea Arabica (Coffee) Seed Extract, Panthenol, Betaine, Hippophae Rhamnoides Fruit Oil, Helianthus Annuus (Sunflower) Seed Oil, Tocopherol, Lecithin, Tocopheryl Acetate, Cetearyl Alcohol, Sucrose Stearate, Sodium Lactate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sorbitan Laurate, Polyglyceryl-4 Caprate, Hydroxyethylcellulose, Pentylene Glycol, Glucose, Polysorbate 20, Potassium Laurate, Dextran, Carbomer, Phenoxyethanol, Ethylhexylglycerin, Sodium Benzoate, Sodium Phytate, Caprylyl Glycol
FORMULATED WITHOUT: fragrance, essential oils, parabens, animal derivatives, formaldehyde-releasers, drying alcohols, phthalates, petrolatum, silicones.
Use Exo-Plex™ Eye Cream every morning and night after your P46 Serum.
Skin Cycling is a strategic, customizable program, created by Dr. Bowe, for cycling through your evening skincare to maximize results, while minimizing irritation. Skin Cycling takes a streamlined, “smarter, not more” approach to skincare, making your products work harder and better for you. With 3.5 billion TikTok views, the viral program has influenced skincare worldwide.
Below is the Classic Skin Cycling Program, which can be customized by adding more Retinal Nights or Recovery Nights depending on your skin's needs.
Night 1: Exfoliation Night
Dr. Bowe opts for chemical exfoliating products over harsh and gritty scrubs. A chemical exfoliating serum can give your skin an immediate glow, prepping you to get the most out of night 2. Exfoliation Night™ Resurfacing + Brightening Serum is specifically formulated to push your skin outside its comfort zone, driving clinically-proven results on night 1 of your Skin Cycling Program, without harming the delicate skin barrier.
Night 2: Retinoid Night
Retinoids are one of the powerful ingredients to include in your Skin Cycling Program. They work to improve skin by breaking down dead skin cells and generating new skin cells—firming and smoothing the look of skin. Your skin’s sensitivity may influence the strength of the retinoid you choose, as some people can tolerate a retinoid more frequently than others. Retinal is the most powerful retinoid you can get without a prescription. Due to Dr. Bowe's expert formulation of Retinal Night™ Advanced 0.1% Retinal Firming Treatment, it's proven to be highly-potent and stable, yet also clinically-proven to be well-tolerated by skin. This makes Retinal Night™ perfect for leveling up any Skin Cycling Program.
Night 3 + 4: Recovery Nights
Hold off on exfoliating acids and retinoids and give your skin a chance to recover. On Recovery Nights, you want to focus on nourishing your skin microbiome and repairing your skin barrier—think hydration and moisture. Dr. Bowe developed Bowe Glowe™ Microbiome Nourishing Cream for every morning, then each night of your Skin Cycling Program, but especially for Recovery Nights to give your skin the hydration and barrier repair it needs. It has been clinically-proven to help repair the skin barrier in just one hour!*
